Por Carlos Benitez1
Esquina de las calles Rivadavia y Rincón. Refugio de la barra de Gardel. Su dueño era el itálico don Bautista. Está ubicado en el barrio de la niñez de José Razzano (el Orientalito) y del célebre gordo Roberto Casaux, futuro experimentado actor cómico. A una cuadra se encuentra la Iglesia Regina Martyrun donde ambos compartían sus habilidades en el Coro.
A la mesa de ese bar concurrió toda la vida Alfredo De Ferrari, quien siempre contribuyó prestándole su viola al futuro célebre dúo Gardel-Razzano.

Con el tiempo el dúo empezó a “echar buena” y eran venerados en el Armenonville, célebre cabaret vidriado de la Av. Alvear. Era un templo de placer, primer ejemplar imitativo del cabaret-chateau parisiense. Ganaron cifras siderales. Allí solamente corría champagne y concurría la elite noble-bohemia de los años 13. Cobraban $70 por noche más las jugosas propinas de los Reservados.
Diametralmente opuesto al Armenonville, que era una ostentación al lujo, se constituía el modesto Café de los Angelitos. Allí concurría el dúo después de las extensas jornadas de trabajo a repartir las ganancias. Razzano era el cajero. Tenía plata por todos los bolsillos y Gardel lo revisaba por sí se guardaba algún billete, sucumbiendo a las tentaciones.
Más tarde, también vuelve a ser punto de encuentro después de actuar en los consagratorios teatros de la calle Corrientes. Allí siempre y desde un principio, aparte del dúo, componían la mesa chica los hermanos Alfredo y Armando de Ferrari, los hermanos Ernesto y Gabriel Laurent y Roberto Casaux. Antonio Sumaje, el aviador, dormitaba en el mateo. Él los transportaba en su coche de caballos, cambiando tiempo después el látigo por el volante. Fueron famosas las partidas de truco donde se ponía en juego quién garpaba los famosos bifes regados con tinto, que Don Bautista hacía marchar. Y sucedió lo previsible. La mesa se fue agrandando. Apareció el pensador Iglesias Paz, Joaquín de Vedia, el célebre jockey Manuel Lema, Manuel Bénard -uno de los creadores de SADAIC y de la ley 11723 de propiedad intelectual entre otras cosas-, un grandote Goliat Luis Ángel Firpo, el Toro Salvaje de las Pampas.
Gardel y Razzano cantaban en las sobremesas trovas de pampa y sierra. E increíblemente van llegando más hombres. Algunos de ellos son los mismos que Gardel oyera con mucho respeto en tiempos idos, cuando no se atrevía a abrir la boca estando ante semejantes troveros. Uno es Ezeiza, el famoso negro Gabino del Heroico Paysandú, otros Curlando, Ramoncito Vieytes, Higinio Cazón, el gurí cantos Aguiar, Ambrosio Ríos. Y un día apareció nada más y nada menos que Don José Betinotti para que el dúo cantara las primicias “Como quiere la madre a sus hijos” y “Tú Diagnóstico”. El Café de los Angelitos se estremecía con esas canciones.
Hay una ocurrencia de Manucho Güiraldes, hermano de Ricardo (autor de Don Segundo Sombra), del pago de Areco donde más de una vez cantó el dúo para el héroe de la novela Don Segundo Ramírez: llegó una vez al Café y vio al gigante boxeador Firpo, a Gabriel Laurent y Alfredo de Ferrari pasando los 120 Kg y palmeándole la espalda a Gardel con más de 100 kg y mirando el cartel del Bar le dijo “a éste café lo llaman de …los angelitos?”.
1 Coleccionista, Presidente del Círculo Gardeliano Bahiense, dueño y fundador del Museo de Radios Antiguas Carlos Gardel de Bahía Blanca.
CAFÉ DE LOS ANGELITOS
(Cátulo Castillo y José Razzano)
Yo te evoco, perdido en la vida
Y enredado en los hilos del humo,
Frente a un grato recuerdo que fumo
Y a esta negra porción de café…
Rivadavia y Rincón… Vieja esquina
De la antigua amistad que regresa,
Coqueteando su gris, en la mesa
Que está,
Meditando en sus noches de ayer…
¡Café de los Angelitos!…
¡Bar de Gabino y Cazón!…
Yo te alegré con mis gritos
En los tiempos de Carlitos
Por Rivadavia y Rincón…
¿Tras de qué sueños volaron?…
¿En qué estrellas andarán?…
Las voces que ayer llegaron
Y pasaron y callaron,
¿Dónde están?…
¡Por qué calles volverán!…
Cuando llueven las noches su frío
Vuelvo al mismo lugar del pasado,
Y de nuevo se sienta a mi lado
Betinoti, templando su voz…
Y en el dulce rincón que era mío
Su cansancio la vida bosteza,
Porque nadie me llama a la mesa
De ayer…
¡Porque todo es ausencia y adiós!…
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Anavar Oxandrolone: Benefits, Side Effects, Dosage, And More
Anavar (Oxandrolone): Benefits, Side Effects, Dosage,
and More
Anavar, the brand name for oxandrolone, is a well‑known anabolic steroid
that has earned popularity among bodybuilders, athletes, and fitness enthusiasts.
Its reputation stems from its relatively mild side‑effect
profile compared to other steroids, making it a frequent choice for those looking to
enhance performance while minimizing health risks.
—
Approved Testosterone Source
Oxandrolone was originally developed as an oral testosterone derivative in the 1960s by the pharmaceutical company
Searle Laboratories. It was approved by regulatory agencies for
specific medical uses such as treating weight loss after surgery
or trauma, and for correcting hormonal deficiencies.
Despite its therapeutic origins, many users now obtain Anavar from non‑prescription sources, which can pose significant legal and safety
concerns.
—
Anavar Benefits
Fat Loss
Anavar stimulates metabolic rate without drastically increasing cortisol levels.
This helps the body burn stored fat while preserving
lean tissue during calorie restriction or cutting phases.
Muscle Gain
Although modest compared to bulking steroids, oxandrolone promotes protein synthesis, leading to noticeable gains
in muscle mass even at low doses.
Strength Building
Users often report a steady increase in strength, allowing for heavier lifts and improved overall performance without the harsh side effects associated
with stronger anabolic agents.
—
Legal Steroid Alternatives That Work
HMB (Beta‑hydroxy beta‑methylbutyrate) – Supports muscle preservation during caloric deficits.
Creatine Monohydrate – Enhances power output and aids
in quick recovery.
Whey Protein Isolate – Provides high‑quality protein for
muscle repair.
These supplements can mimic many of Anavar’s benefits
without the legal complications of steroid use.
Mild Side Effects
Less Liver Toxic
Because oxandrolone is a 17α‑alkylated compound, it
does exert some hepatic stress; however, at recommended
doses (20–30 mg/day), liver enzyme elevations are typically mild and reversible.
No Gynecomastia or Water Retention
Unlike many anabolic steroids, Anavar has low estrogenic activity,
so users rarely experience breast tissue swelling
or fluid retention.
Less Androgenicity
Its androgenic potential is relatively weak, reducing the likelihood of
symptoms such as acne or facial hair growth in men and virilization in women.
Less Problematic for Women
Due to its lower androgenic effect, Anavar is considered one of the safest
anabolic steroids for female users, provided dosing stays conservative (5–10 mg/day).
Increased Recovery, Endurance, and Speed
Users often notice faster muscle recovery between sessions, improved cardiovascular endurance during workouts, and a quicker overall training tempo.
Pronounced Pumps
Oxandrolone can cause significant vascularity, giving athletes a “pump” effect that is
both functional and visually appealing.
—
Anavar Side Effects
While mild compared to other steroids, anavar dosage for women bodybuilding still carries risks:
High LDL Cholesterol – Can raise bad cholesterol levels if not monitored.
Suppressed Testosterone – Prolonged use may lower
natural testosterone production.
Kidney Damage – Rare but possible with high doses or extended
cycles.
Hair Loss – Genetic predisposition can be exacerbated by anabolic steroid use.
How to Prevent Hair Loss on Anavar
Use Finasteride or Dutasteride – These medications inhibit DHT
production, the hormone responsible for androgenic alopecia.
Maintain a Balanced Diet – Adequate protein, zinc, and biotin support hair health.
Limit Oxandrolone Exposure – Stick to lower doses (≤20 mg/day) whenever possible.
Anavar Legality
In many countries, including the United States, oxandrolone
is classified as a Schedule III controlled substance.
Possession without a prescription can lead to legal penalties ranging from fines to imprisonment.
Always verify local regulations before purchasing or using
Anavar.
—
Top 3 Legal Anavar Brands
Pharmaceutical Oxandrolone – Prescribed by licensed physicians for medical conditions.
UGL (United Global Labs) Anavar – A reputable source offering high‑purity compounds.
Crestorox – Known for strict quality control and reliable delivery.
Anavar Dosage
For Men
20–30 mg/day split into two doses.
Typical cycle length: 4–6 weeks.
For Women
5–10 mg/day, ideally divided twice daily.
Cycle duration: 4–6 weeks to avoid virilization.
Anavar PCT
After a cycle, natural testosterone recovery is essential.
Common post‑cycle protocols include:
Nolvadex (Tamoxifen) – 20 mg/day for 2–3 weeks.
DHEA – 25–50 mg/day to aid adrenal function.
Anavar Reviews
Users consistently report improved muscle definition, modest
weight gain, and a noticeable boost in training
performance. Negative feedback often centers on cholesterol changes
and the need for careful monitoring of liver enzymes.
—
Where to Buy Anavar
Licensed Pharmacies – Only with a valid prescription.
Reputable Online Vendors – Verify certifications and customer reviews before purchase.
How to Avoid Being Scammed When Purchasing Anavar
Check for third‑party lab test results.
Look for secure payment options (e.g., PayPal).
Read user testimonials from multiple platforms.
Confirm shipping privacy and packaging quality.
Price of Anavar
Prices vary based on purity, brand, and quantity. Expect:
Pharmaceutical: $80–$120 per 100 mg vial.
UGL/Other: $50–$90 per 100 mg vial.
Bulk Packages: Discounts for larger orders.
Pharmaceutical Anavar
Prescription‑grade oxandrolone contains no fillers and meets
stringent manufacturing standards, ensuring safety when used under medical supervision.
—
UGL Anavar
UGL provides high‑quality oxandrolone with lab verification. It is a
popular choice among bodybuilders seeking reliable potency.
—
Temporary or Permanent Gains
Most gains achieved on Anavar are sustainable
if combined with proper nutrition and training. However, muscle mass may regress without ongoing stimulus or
continued steroid use, as the drug itself does not create lasting changes in hormone levels.
—
Anavar on an Empty Stomach
Taking Anavar before meals can improve absorption due to reduced competition from other compounds.
Nonetheless, some users experience mild gastrointestinal discomfort; taking it with a small snack mitigates this risk.
—
“My Anavar Is Not Working”
Possible reasons include:
Incorrect dosage or timing.
Insufficient protein intake.
Inadequate training stimulus.
Poor sleep and recovery habits.
Review your protocol and adjust as needed.
Anavar vs. Trenbolone
Trenbolone offers greater strength and mass gains but carries a higher risk of liver toxicity, cardiovascular strain, and severe mood changes.
Anavar is preferred for those prioritizing safety and moderate results.
—
Anavar vs. Clenbuterol
Clenbuterol is a thermogenic stimulant with no anabolic effects; it burns fat rapidly but can cause tachycardia and tremors.
Anavar provides both muscle preservation and fat loss in a single compound, making it more
versatile.
—
Anavar and Alcohol Consumption
Alcohol can further stress the liver, especially when combined with oxandrolone’s hepatic load.
Limit alcohol intake during cycles to reduce risk of hepatotoxicity.
—
Diet on Anavar
Protein: 1.2–1.5 g per pound of body weight.
Carbohydrates: Moderate intake to fuel workouts.
Fats: Healthy fats for hormone synthesis.
Micronutrients: Focus on vitamins D, B12, and zinc.
Anavar and Drug Tests
Oxandrolone is detectable in standard drug panels (e.g.,
urine testosterone tests). Users should be aware of potential positive results during employment or athletic eligibility testing.
—
Anavar and Sleep Quality
While some users report improved sleep due to increased energy
levels, others experience insomnia if dosed late.
Schedule dosing early in the day to minimize disruptions.
—
Anavar Supplementation All Year Round
Because oxandrolone is not a long‑term therapy, it should be used only during defined cycles.
Continuous use can lead to hormone suppression and organ damage.
—
“Anavar Made Me Gain Fat”
Fat gain on Anavar may result from overfeeding or improper macronutrient
ratios. Ensure caloric intake aligns with training demands; excess
calories will convert to fat regardless of steroid use.
—
Summary
Oxandrolone (Anavar) offers a balanced blend of muscle preservation, moderate strength
gains, and minimal side‑effect profile when used responsibly.
Its legal status, potential for abuse, and health risks necessitate careful
dosage planning, post‑cycle support, and adherence to medical guidance.
By integrating proper nutrition, training, and recovery protocols, users can maximize Anavar’s benefits
while minimizing adverse outcomes.
—
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Anabolic Steroids: Uses, Abuse, And Side Effects
An In‑Depth Guide to Anabolic Steroids
Anabolic steroids (often called “anabolics”) are synthetic compounds that mimic the effects of the male
hormone testosterone. They’re used medically for conditions such as delayed puberty, muscle wasting disorders, and severe anemia, but many athletes, bodybuilders, and gym enthusiasts misuse them
to boost muscle mass and performance. This guide breaks
down everything you need to know—definitions, uses, risks, legal status, and safer alternatives—in a concise, easy‑to‑digest format.
—
1. What Are Anabolic Steroids?
Term Meaning
Anabolic Builds up tissue (e.g., muscle).
Steroid Chemical class of hormones derived from cholesterol.
Testosterone‑based Most steroids are synthetic analogues or derivatives
of testosterone, the male sex hormone.
Key Components
Synthetic Testosterone Analogues: e.g., nandrolone,
stanozolol.
Esterified Forms: Increase duration; common in oral pills
and injectable oils.
2. How Do They Work?
Binding to Androgen Receptors (AR): Steroids enter cells → bind AR → complex travels to nucleus → influences gene transcription.
Protein Synthesis: Upregulates genes for ribosomal proteins, growth factors
→ increases muscle cell size.
Nitrogen Balance: Enhances retention of nitrogen (protein building blocks) →
positive nitrogen balance.
Red Blood Cell Production (Erythropoiesis):
Some steroids stimulate erythropoietin production → more
oxygen delivery to muscles.
3. Key Pharmacokinetic Properties
Parameter Typical Values Notes
Absorption Oral bioavailability ~30–50% (due to first-pass metabolism).
Lipophilic; can be taken with fats for better absorption.
Distribution High plasma protein binding (~80–95%).
Vd ~1–3 L/kg depending on steroid.
Metabolism Hepatic via CYP450 (primarily 3α/4β-reductase).
Metabolites are often inactive.
Excretion Urinary elimination of metabolites; biliary excretion minimal.
Half-life varies from 12–48 hours.
—
2. Potential Interaction with “Drug X”
2.1 Pharmacological Profile of Drug X
Mechanism: Selective inhibition of the cytochrome P450 isoenzyme CYP3A4,
leading to reduced hepatic metabolism of drugs that are CYP3A4 substrates.
Therapeutic Use: Antiviral therapy for chronic hepatitis B (used in combination with a nucleoside analogue).
Side‑effects: Mild GI upset, dizziness; rare
hepatotoxicity reported when combined with other CYP3A4 inhibitors.
2.2 Mechanism of Interaction
Drug Primary Metabolic Pathway Interaction with Drug X
Corticosteroid (prednisolone) Mainly via CYP3A4; also CYP1A2, CYP2D6 Inhibition –
leads to increased plasma levels and prolonged action.
Non‑steroidal anti‑inflammatory (ibuprofen) Primarily glucuronidation (UGT enzymes);
minimal CYP involvement No significant interaction – Drug X
unlikely to alter ibuprofen pharmacokinetics.
Corticosteroids: Inhibition of CYP3A4 by Drug X raises steroid concentrations,
raising the risk for side effects such as immunosuppression,
hypertension, hyperglycemia, and osteoporosis.
NSAIDs (ibuprofen): Metabolism largely independent of CYP
enzymes; thus no major drug‑drug interaction expected.
2. Impact of Pharmacogenomic Variants on Drug Response
Gene Variant Frequency in UK Population Effect on Metabolism/Response
CYP2D6 1/4 (heterozygous loss‑of‑function) ~15 % have one
nonfunctional allele Decreased metabolism of propranolol → ↑ plasma concentration, ↑ risk of bradycardia/AV block
CYP3A5 3/3 (no functional protein) ~70 % homozygous for *3 ↓ CYP3A activity → ↓ propranolol clearance; may require dose adjustment
SLC22A1 (OCT1) Loss‑of‑function variant (e.g., p.Arg61Cys) ~10–15 % carry a loss‑of‑function allele
Reduced hepatic uptake of propranolol → ↑ plasma levels, ↑ systemic
exposure
UGT2B7 Variant rs7439366 (G-allele associated with increased activity) ~20 % heterozygous carriers Enhanced glucuronidation →
faster clearance; may lower steady‑state concentration
Practical Implications
Patients carrying high‑activity UGT2B7 or UGT1A9 variants
– May clear propranolol more rapidly, potentially requiring a
higher dose to maintain therapeutic plasma levels.
Patients with loss‑of‑function CYP3A4/CYP2D6 variants
– Reduced metabolism can lead to higher drug exposure and increased risk of adverse effects (e.g.,
bradycardia, hypotension). Dose reduction or more frequent monitoring
may be warranted.
Drug–drug interactions
– Concomitant use of strong CYP3A4 inhibitors (e.g., ketoconazole) can elevate propranolol levels even in patients with
normal metabolism. Conversely, strong CYP3A4 inducers (e.g., rifampicin) may lower plasma concentrations.
5. Practical Implementation for the Clinic
Step Action
1. Baseline Record heart rate, blood pressure, ECG. Note
any contraindications (severe bradycardia, heart
block).
2. Start dose 0.25 mg PO BID (or 5 mg PO QD for immediate-release)
in the morning.
3. Follow‑up Reassess vitals after 1–2 weeks; titrate by 0.25 mg every 2 weeks if tolerated.
Max up to 2 mg BID.
4. Monitor Watch for dizziness, fatigue, hypotension, especially
when standing.
5. Educate Advise on slow rising from bed/chairs; avoid sudden position changes.
Rationale:
The chosen schedule balances efficacy (controlling arrhythmias and palpitations) with safety (minimizing orthostatic hypotension).
The gradual titration allows early detection of adverse effects,
especially in patients prone to blood pressure dips.
—
3. Adverse‑Effect Profile & Risk Stratification
Category Potential Adverse Effects Key Risk Factors
Cardiovascular Orthostatic hypotension, tachycardia, arrhythmias (especially at high doses) Elderly, chronic hypertension, diuretics, beta‑blocker withdrawal
Central Nervous System Dizziness, confusion, blurred vision, impaired concentration, seizures in severe cases Renal insufficiency
(slower clearance), concomitant CNS depressants
Renal Elevated serum creatinine, electrolyte disturbances (hypokalemia) Pre‑existing CKD, diuretics, ACE inhibitors/ARBs
Gastrointestinal Nausea, vomiting (rare) Rare; more commonly seen with higher
doses
Others Skin flushing, mild pruritus Rare
—
4. Practical Recommendations for the Emergency Physician
Step What to Do Why
1. Verify indication & contraindication Confirm
that the patient truly needs a diuretic (e.g., fluid overload).
Exclude absolute contraindications: severe hypotension, anuria,
known allergy, pregnancy. Avoid unnecessary or harmful therapy.
2. Assess baseline vitals & labs BP, HR, electrolytes (Na⁺, K⁺), creatinine, eGFR.
Establish a reference point and identify high‑risk
patients.
3. Decide on drug For most acute settings: furosemide (IV).
Furosemide is potent, fast‑acting, and well‑studied.
4. Calculate dose IV: 10–20 mg initial; repeat
as needed every 30 min to 1 h until desired
effect. Start low, titrate up based on response.
5. Monitor response Urine output, weight change, signs
of dehydration or overload. Adjust dosing accordingly.
6. Watch for side‑effects Electrolyte imbalances (K⁺ loss), ototoxicity with high cumulative doses.
Check electrolytes after 24 h; correct as needed.
7. Record everything Dose, time, response, labs. Ensures continuity and safety.
—
Final Take‑away
Start low, go slow.
Titrate based on objective measures (output, weight,
labs).
Keep a meticulous log – dose, time, response, side‑effects.
Re‑evaluate at least every 12–24 h or sooner if the patient’s status changes.
This systematic, evidence‑based approach—grounded in current guidelines and meta‑analytic data—helps clinicians safely manage diuretic therapy while minimizing adverse outcomes.
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